Breaking Up Just Got Easier to Do

نویسندگان

  • Hannah L. Klein
  • Lorraine S. Symington
چکیده

The SLX4 protein functions as a platform for catalytic subunits of structure-specific endonucleases. Findings reported in Cell (Fekairi et al., 2009; Svendsen et al., 2009) and in Molecular Cell (Andersen et al., 2009; Muñoz et al., 2009) now identify the human SLX4 and show that in association with the SLX1 endonuclease it directs the symmetric cleavage and resolution of Holliday junctions.

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عنوان ژورنال:
  • Cell

دوره 138  شماره 

صفحات  -

تاریخ انتشار 2009